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New Solution for Anti-aging

By: Shyam Gupta, PhD, and Linda Walker
Posted: March 8, 2011, from the March 2011 issue of GCI Magazine.

Loss of internal cellular pressure due to water loss causes osmotic stress, resulting in wrinkled, saggy skin. And the application of osmoprotectants—small molecules that help organisms survive extreme osmotic stress—has clear implications for multifunctional skin care.

Introducing new technologies is crucial to connect with beauty consumers always on the lookout for the latest thing, and the more unique the technology, the deeper the potential brand/consumer connection. Osmoprotection, a recently recognized new therapeutic methodology, offers new solutions for topical problems that relate to skin aging—including collagen synthesis, intracellular inflammation prevention, antioxidant protection, free radical scavenging, de novo DNA synthesis, control of wrinkles and fine lines, skin brightening, age spot reduction and acne.

Cells must maintain an optimal balance of water to stay plump and healthy. Imagine a face drawn on a balloon and filled with water. The face will look plump and youthful as the water keeps pressure on the balloon’s inside surface. But if the water were to slowly leak (osmosis) out of the balloon, the drawn face would increasingly look wrinkled, tired, saggy and aged.

Similar loss of internal cellular pressure due to water loss causes osmotic stress, resulting in aged looking skin.

Osmoprotectant ingredients are the wave-of-the-future answer to this critical cellular water pressure balance.

Osmoprotectants are small molecules that help organisms survive extreme osmotic stress. These molecules accumulate in cells, and balance the osmotic difference between the cell’s surroundings and intracellular fluid. While use of humectants and emollients has been an age-old practice, the application of osmoprotection for multifunctional skin and hair care formulations is relatively new.