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Genomics—Advanced Tools to Combat Aging

By: Steve Herman
Posted: June 3, 2010, from the June 2010 issue of GCI Magazine.

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There’s more, of course: Lancôme Genifique Youth Activating Concentrate, Olay Pro-X Deep Wrinkle Treatment, L’Oréal’s Biotherm Skin Vivo, Estée Lauder Advanced Night Repair Synchronized Recovery Complex with Chronolux Technology … genomic applications are far from an obscure backwater of research labs.

For years the strongest area of the beauty market has been antiaging products. Traditional formulation and clinical methods have been used to develop and test most of the current products. Increasingly, products on the market are created and substantiated by genomic tools made technically and economically efficient by advances such as the gene chip. The science seems daunting, but it is essentially just a refined way of looking at what you always cared about—wrinkles, hydration, pigmentation. The goal is the same, youthful skin; it is just a quantum leap in technology that has brought the goal closer for consumers.

Acknowledgements

In March, the New York Society of Cosmetic Chemists (NYSCC) featured back-to-back presentations on genomics and aging skin from Anna Jelaso Langerveld and Helen Knaggs, which inspired this column. Thanks to them both for making their presentations available: AJ Langerveld, “Applications of Genomics Tools for Personal Care Product Development,” NYSCC Educational Hour, March 3, 2010, and H Knaggs, “Aging and Genes—The Link with Skin,” NYSCC, March 3, 2010.

References

  1. J Watson, The Double Helix, Norton, 1980
  2. F Crick, Central Dogma of Molecular Biology, Nature 227 561–563
  3. J Tiesman, From bench to beauty counter: practical applications, J Drugs Dermatol 8 (Suppl) (2009)
  4. www.genenames.org
  5. S Herman, Wrinkle Free—Not Just for Shirts!, GCI magazine (Nov 2005)
  6. www.pgdermatology.com/downloads/documents/Genomics-of-Skin-Aging-Practical-Applications.pdf
  7. www.nuskin.com/en_US/home.html
  8. www.elinaskincare.com (All sites accessed Apr 16, 2010)

Steve Herman is president of Diffusion LLC, a consulting company specializing in regulatory issues, intellectual property, and technology development and transfer. He is a principal in PJS Partners, offering formulation, marketing and technology solutions for the personal care and fragrance industry. He is an adjunct professor in the Fairleigh Dickinson University Masters in Cosmetic Science program and is a Fellow in the Society of Cosmetic Chemists.