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Matrixyl Neolide: Croda’s Next-Gen Encapsulated Peptide for 15-Day Sustained Release

When used with microneedling, the active showed a 31% increase in collagen III compared to a placebo plus microneedling.
When used with microneedling, the active showed a 31% increase in collagen III compared to a placebo plus microneedling.
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Clinical data indicates a 25% increase in visible skin firming within two weeks compared to day zero (pictured).Clinical data indicates a 25% increase in visible skin firming within two weeks compared to day zero (pictured).CrodaCroda Beauty Actives has launched Matrixyl Neolide, an evolutionary update to its established Matrixyl peptide line. 

This new iteration utilizes a patented encapsulation technology designed to protect the peptide within formulations and provide a controlled release over 15 days.

The ingredient is positioned for use in advanced skin care, professional protocols and post-aesthetic treatment recovery care. 

Clinical data indicates a 25% increase in visible skin firming within two weeks compared to day zero (pictured is day 15).Clinical data indicates a 25% increase in visible skin firming within two weeks compared to day zero (pictured is day 15).CrodaKey technical and performance data include:

  • Efficacy: Clinical data indicates a 25% increase in visible skin firming within two weeks compared to day zero (p<0.01).
  • Synergy: When used with microneedling, the active showed a 31% increase in collagen III compared to a placebo plus microneedling.
  • Sustainability Profile: The active is derived from 99.79% natural-origin content according to ISO 16128. It reports a 43% lower carbon footprint than the original Matrixyl.
  • Compliance: The product is TFAs-free, vegan-suitable, and RSPO-compliant.
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