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Top 11 Hotspots for Future Beauty Innovation from the 2025 SCC Annual Scientific Meeting

Epigenetics and biomimetics were two buzz words at this year's meeting. Here, Paul Lawrence, Ph.D., of Biocogent, presented on epigenetics and miRNA to bolster or intercept skin cell 'text messages.'
Epigenetics and biomimetics were two buzz words at this year's meeting. Here, Paul Lawrence, Ph.D., of Biocogent, presented on epigenetics and miRNA to bolster or intercept skin cell "text messages."

The Society of Cosmetic Chemists' 79th Annual Scientific Meeting (SCC79), held Dec. 16 and 17, 2025, in NYC, painted a vibrant picture of future hotspots for beauty innovation, inspiring some 800+ registered attendees. Following is an overview of what we observed; Editor's note: This is by no means comprehensive.

1. Biomimetics and Epigenetics

- Empowering the body's own repair mechanisms
- Epigenetics and small RNA-based actives to trigger pathways for longevity, health, autophagy, HA in skin, etc.
- Understanding hair biology to build cumulative repair effects
- miRNA mimics and antagomiRs to intercept or bolster "text messages" to cells

2. Efficacy Testing and Claims Support

- Advancing skin models to measure active benefits
- Single-cell transcriptomics to replicate cell communication (to measure benefits of actives)
- Vibrational spectroscopy to evaluate skin/scalp physiology
- Reconstructed pigmented epidermis to measure pigment changes
- Texture analysis
- Confocal Raman to measure hydrogen bond strength in hair (for bond repair claims)
- Triculture model with sensory neurons, melanocytes and keratinocytes (to measure neurocosmetics)

3. Dermocosmetics and Skin Wellness

- Dermatology meets AI; AI-designed peptides
- Skin disorders in diverse patients
- Secretome for skin health and longevity
- Empowering skin's native mechanisms (biomimetics)
- Microbiome
- Anti-wrinkle effects
- Neuron-skin communication
- Intercelluar communications and messaging (epigenetics)

4. Hair Health, Bonding and Bioprotection

- AI-designed peptides
- Biosilk peptides
- Measuring bonding claims (hydrogen networks)
- Hair damage repair
- Bioprotection as a new category (protecting against pollution, blocking buildup, heat, breakage; improving thickness)
- Reduced hair fall and improved density

5. Sun Care and SPF Testing, Optimization

- SPF testing - new method comparisons
- Buzz around DSM-Firmenich's progress with the U.S. Food and Drug Administration (FDA) to endorse bemotrizinol as an approved sunscreen active
- Multifunctionals in sunscreens (e.g., ingredients that are antioxidants + SPF boosters in one)
- Skinification of sunscreens (i.e., multifunctional sun protection)
- Optimization via production methods and spreading
- Efficacy of films

6. Natural and Multifunctional

- Natural SPF booster + antioxidant
- Bio-based preservative with microbiome-boosting benefits
- Dispersing and emulsifying
- New data showing skin care ingredients also improve hair/scalp
- Natural cellulose paper awarded

7. Sustainability and Biotechnology

- Algae-derived ink to replace Carbon Black, produced using biomass as feedstock and demonstrating carbon-sequestering capabilities
- Recombinant hirudin peptide expressed from algae
- Eco-friendly hair conditioning
- Sophorolipids
- LCA assessments
- Enzymatic extraction of upcycled ingredient for color + care benefits
- Recombinant collagen
- Biosynthesis of terpenoids
- Oxyresveratrol (in Chinese biotech session)
- PFAS-free peptide

Honorable Mentions

8. Hair Growth and Maintenance

- Focus on vascularization around follicles via the role of glypicans
- Reducing hair fall and thinning
- improving thickness

9. Inclusivity and Diversity

- Targeting hyperpigmentation and dark spots/brightening
- Skin conditions in different skin types
- Color matching
- Sun protection for deeper skin tones

10. Tattooed Skin Care

-Featured keynote

11. Prebiotics

-Paper awarded

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