This month, Exsymol launched its latest and greatest anti-aging ingredient during Cosmet'Agora: Alistisilane, merging decarboxycarnosine — a peptide — with biofunctional silicium to synergistically deliver benefits including enhanced skin elasticity, reduced wrinkles and improved radiance. The active is 99.1% natural, per ISO 16128, and according to Exsymol, it can integrate into formulations for advanced skin care applications.
Alistisilane's Mechanisms of Action
Per the company, Alistisilane takes a three-step approach to rejuvenate and revitalize skin. Proven mechanisms include:
- Protecting against glycation: Decreasing advanced glycation end-products (AGEs) by 50% and curbing collagen degradation by 30%, to preserve skin structure;
- Restructuring the extracellular matrix: Boosting collagen density by 28% and enhancing fibronectin levels by 40%, stabilizing blood vessels and aiding skin regeneration; and
- Restoring vascularization: Promoting a 24% increase in endothelial cell proliferation and improving revascularization by 84% in just two hours.
Clinical Skin Benefits
A clinical study of 30 women, ages 40 to 60, showed that application of the product over a period of 56 days, improved:
- Facial contour: With a 10% reduction in sagging;
- Skin smoothness: With a 16% decrease in roughness;
- Wrinkles: With a 20% reduction in wrinkle depth; and
- Radiance: With a 43% enhancement in complexion glow.
Revascularizing, Rejuvenating the Skin
As Exsymol explained, blood vessels play a vital role in nourishing skin cells by delivering oxygen and nutrients while providing structural support to prevent sagging. However, with age and external aggressors, vascular regression occurs, leading to dermal papillae loss, dermo-epidermal flattening and visible signs of aging, such as wrinkles and dullness. By restoring vascularization, Alistisilane addresses these foundational aspects of skin health.
Alistisilane’s proven efficacy and multifunctionality make it a compelling solution for rejuvenating and revitalizing aging skin, the company notes. Through its advanced peptide and silanol technologies, the ingredient is designed to deliver comprehensive benefits to maintain a youthful, radiant appearance.
