BASF scientists and research partners will spotlight two emerging approaches to skin care at the 36th IFSCC Congress, taking place September 28–October 1 in Perth, Australia. Beyond sustainable extraction technologies, the company will present research into collagen hybridizing peptides (CHPs) and bio-based polysaccharides, exploring how targeted peptide technologies and biopolymer systems could support skin regeneration, hydration and barrier function.
The collagen study focuses on CHPs, a class of bioactive peptides inspired by biomedical research that can recognize and bind to damaged collagen structures.
In a clinical study, BASF researchers reported that their lead CHP candidate selectively targeted altered collagen, stimulated procollagen I production, supported tissue-repair processes and significantly reduced damaged collagen.
AI-driven molecular modeling was used to support the research, pointing to a potential strategy for addressing visible signs of skin aging through targeted collagen repair and improved cellular communication.
In a separate collaboration with Stanford University, BASF scientists investigated how bio-based polysaccharides form functional films on skin.
The researchers found that molecular entanglement and crystallization influence film formation and water transport through the stratum corneum, while the bio-based additives improved hydration retention, emollient penetration and resistance to drying-induced stress while maintaining skin barrier function.
