Silab has developed Cicactyl, a natural-origin active ingredient designed to support the repair of wounded or damaged skin by accelerating the skin’s proliferation phase during healing. The ingredient is formulated to improve the efficiency of skin recovery processes, with a targeted focus on enhancing barrier restoration from the earliest stages of application.
Clinical studies conducted on adult Caucasian subjects with damaged skin demonstrated that Cicactyl begins acting from initial application, contributing to faster recovery of the skin barrier. Observed benefits included reduced erythema, dryness and scab formation, indicating improved overall healing quality.
Mechanistically, in vitro research shows that Cicactyl influences key biological events involved in the proliferation phase of wound healing. These include stimulation of granulation tissue formation, enhancement of vascular network development, support of re-epithelialization, and reduction of inflammation. Together, these multi-target actions contribute to an improved rate of skin repair.
The active ingredient is derived from carob gum (Ceratonia siliqua) and is standardized to be 85% purified galactomannans, with 100% natural origin content according to ISO 16128. Research indicates that the efficacy of Cicactyl is linked to the size, structure and botanical origin of its galactomannans, which exhibit strong affinity for lectin receptors associated with healing pathways.
Silab has also emphasized sustainable sourcing practices, establishing partnerships with certified organic suppliers across the Mediterranean basin to ensure controlled quality and supply of carob gum. The ingredient is produced as a preservative-free powder (INCI: galactomannan and maltodextrin) recommended for dermo-cosmetic formulations at usage levels of 0.05-1.0%.
Safety evaluations indicate that Cicactyl is well tolerated on compromised skin, including sensitive conditions. It is positioned for use in healing-oriented facial and body care products for adults, including pregnant and breastfeeding women, as well as infants.
