
Givaudan Active Beauty presents PrimalHyal NeuroYouth, an innovative complex based on low molecular weight hyaluronic acid and amino acids designed to address a recently identified skin-aging pathway, defined by the company as Neuro Skin Aging. This new complex reverses the neuro-aging pathway, enabling neuronal growth and density-related parameters (with a 28% increase in nerve fiber count and a 29% increase in their length), enhancing neuronal communication pathways through NGF-like activity, reactivating neuronal mitochondria's energetic efficiency.
By supporting the skin’s neuro-sensory environment and helping to preserve skin homeostasis, PrimalHyal NeuroYouth contributes to stronger-looking, healthier and more comfortable skin, while enhancing its perceived capacity to sense and interact with its environment. By restoring function and neuronal communication, the complex opens up a new frontier in skin health and well-aging.
Inspired by microneedling, PrimalHyal NeuroYouth is a unique HA-based amino acid complex designed to enhance skin bioavailability and the biological relevance of amino acids.
Clinical studies conducted on more than 120 volunteers demonstrate that PrimalHyal NeuroYouth delivers visible and measurable anti-aging benefits, including(1) :
- Apparent skin age reduced by over 5 years
- Visible reduction in wrinkles and fine lines
- Improvement in dermal tension and skin firmness
- Touch perception restored by up to 30 years
- Perceivable improvement of pleasant sensations
“Beyond aesthetics, PrimalHyal NeuroYouth redefines skin ageing from a skin health perspective,” explains Romain Reynaud, R&D Director at Givaudan Active Beauty. “By addressing ‘Neuro Skin Ageing’, it offers new perspectives for the positioning of silver age, prejuvenation and skin resilience concepts, where neurological health becomes a key pillar of youthful skin.”
(1) In addition to the biological evaluations, these benefits were also perceived by 145 female beauty consumers who participated in Givaudan Active Beauty’s Home Usage Test, proven by a disruptive implicit methodology.










